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The Lancet
- [Comment] Offline: Climate and health—time to step up our activism
It is official: global warming is accelerating. In a paper published in Geophysical Research Letters in March, 2026, Grant Foster and Stefan Rahmstorf strip out the noise of natural variability in tem … - [World Report] Lebanon's health system: a silent casualty of war
Lebanon's already weakened health system is overwhelmed, under-resourced, and increasingly attacked by the Israeli army. Amelie David reports from Lebanon. - [Comment] Fabricated references: a new threat to editorial integrity
In this issue of The Lancet, Topaz and colleagues1 report the first systematic evaluation of the authenticity of references. The authors initially identified 125 615 773 references from 2 471 758 pape … - [Articles] Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme
Introduction of the RTS,S malaria vaccine in routine immunisation programmes was associated with a significant reduction in mortality in young children, averting about one in eight deaths, in areas wi … - [Articles] Enpatoran, a Toll-like receptor 7/8 inhibitor, in moderate-to-severe systemic lupus erythematosus: findings from Cohort B of a multicentre, international, double-blind, placebo-controlled dose-finding phase 2 trial
In this study of participants with moderate-to-severe SLE, enpatoran improved BICLA response rates versus placebo; however, the primary objective of a statistically significant dose-dependent effect o …
New England Journal of Medicine
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BMJ
- Hantavirus: French and US nationals test positive as cruise ship docks in Canary Islands
One French woman and one US national who disembarked from the cruise ship MV Hondius have now tested positive for hantavirus.Another US national was also reported as showing symptoms of possible infec … - Hantavirus: people are betting on a pandemic breaking out
A risky gamble?It’s certainly a controversial one. But the practice of staking money on the likelihood of disease outbreaks or future pandemics is a growing trend, with gamblers flocking to online pre … - Autism intervention meta-analysis of early childhood studies (Project AIM): updated systematic review and secondary analysis
In this paper by Sandbank and colleagues (BMJ 2023;383: e076733, doi:10.1136/bmj-2023-076733, published 14 November 2023), supplementary tables S3 and S4 included limited reference information. These … - Struck-off doctors are finding jobs in other EU countries, investigation finds
Doctors who have been struck off in one European Union country are continuing to practise in another, an investigation has found.News outlets De Tijd, Le Monde, and France Télévision found that four F … - Trump mental health: 30 senior US doctors declare president mentally unfit
Thirty US psychiatrists and other doctors specialising in mental health have signed a statement declaring President Donald Trump mentally unfit to serve, warning that his ability to launch nuclear wea …
JAMA
- Does This Child Have a Concussion?
This Rational Clinical Examination reviews the diagnostic accuracy of symptoms and signs observed in the initial evaluation of a child or adolescent who may have had a concussion. - Cost-Effectiveness of ApoB, Non–HDL-C, and LDL-C Goals for Primary Prevention Lipid-Lowering Therapy
This economic evaluation examines the cost-effectiveness of low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol, and apolipoprotein B goals for lipid-lowering therapy in a co … - Navigating Thyroid Hormone Deprescribing in Older Adults
Thyroid hormone medication use is common, with levothyroxine ranking among the 3 most commonly dispensed medications in the US and Europe. Older age is an independent predictor of thyroid hormone init … - Skinny Labels at the Supreme Court—Generic Competition, Patent Inducement, and Affordable Medicines
This Viewpoint discusses use of skinny labeling to reduce the price of brand-name drugs, impediments to timely generic market entry and affordability, and inducement liability that causes marketing un … - Management of Crohn Disease in Adults
This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterology’s 2025 recommendations on management of Crohn disease in adults.
