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The Lancet
- [Articles] Efficacy and safety of cefepime–nacubactam and aztreonam–nacubactam compared with imipenem–cilastatin for complicated urinary tract infection or acute uncomplicated pyelonephritis (Integral-1): a double-blind, randomised phase 3 trial
Cefepime–nacubactam and aztreonam–nacubactam are potential treatment options for Gram-negative cUTI and acute uncomplicated pyelonephritis, including infections caused by antimicrobial-resistant strai … - [Perspectives] Thu-Anh Nguyen: building equitable access to health
“In Viet Nam, health challenges are rarely abstract”, says Thu-Anh Nguyen, Director of the University of Sydney Vietnam Institute (SVI) and Professor in Global Health at the University of Sydney, Aust … - [Perspectives] Digitising the thymus
For decades, the thymus has been regarded as a vestigial organ of childhood, essential for T-cell education early in life, but thought to lose relevance as it involutes into fatty tissue after adolesc … - [World Report] Cleft surgery in Peru
Peru is expanding access to surgery and care for patients with cleft conditions in remote areas through intensive capacity-building led by local volunteers. Jacqui Thornton reports. - [World Report] The medicine of…prisons
As part of a series on medicine in unusual settings, Talha Burki takes a look at medical practice in UK prisons.
New England Journal of Medicine
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BMJ
- Improving awareness and care in polyendocrine metabolic ovarian syndrome (formerly polycystic ovary syndrome)
Polyendocrine metabolic ovarian syndrome (PMOS), formerly polycystic ovary syndrome (PCOS), is one of the commonest endocrine disorders in women of reproductive age, with a global prevalence of 7-12%, … - Restoring certainty to global health regulation
An acknowledgement to Elize Massard da Fonseca was omitted in this editorial by Y Tony Yang and colleagues (BMJ 2026;393:s814; doi:10.1136/bmj.s814). The online version has been corrected. - Ambiguous guideline recommendations harm patient care
Guidelines should help clinicians and patients make better decisions, but too often they do the opposite. Providing recommendations that are vague, outdated, or inactionable can harm patients by causi … - PCOS name change to PMOS must be managed to avoid confusing patients, says expert
Polycystic ovary syndrome (PCOS) has been renamed polyendocrine metabolic ovarian syndrome (PMOS), an article published in the Lancet has advised.1However, experts warn that care must be taken to intr … - Gaza doctors documentary dropped by BBC wins Bafta award
A documentary detailing Israeli military attacks on hospitals and ambulances in Gaza and the deaths and injuries of Palestinian healthcare workers has won a British Academy of Film and Television Arts …
JAMA
- Prevention of Respiratory Syncytial Virus–Related Hospitalization in Newborns—Reply
In Reply We appreciate the opportunity to respond to comments by Dr Manzoni and colleagues about our study comparing passive infant immunization with nirsevimab and maternal immunization with the RSVp … - Endometrial Cancer: A Review
This review discusses the epidemiology, clinical presentation, diagnosis, surgical management, histopathologic and molecular characteristics, and adjuvant treatment for endometrial cancer. - “Hooch,” “Home Brew” and Copper
The toxicity of many of the heavy metals has been known for generations, yet these substances have not been regarded as a menace to human health except in limited instances where industrial conditions … - International Reference Pricing Across Medicare and Medicaid
This Viewpoint discusses 3 US Centers for Medicare & Medicaid Services (CMS) drug pricing models and how a pivot toward international reference pricing could affect consumers, manufacturers, and d … - Real-World Outcomes of Transcatheter Tricuspid Valve Replacement
This retrospective cohort study examines the safety, efficacy, and patient-reported outcomes of device-enabled transcatheter tricuspid valve replacement in patients with symptomatic, severe tricuspid …
